Advanced Diagnostic Microbiology:
The course describes the latest developments and research in the field of diagnosis of infectious microbial diseases and the importance of following them up and benefiting from their applications. The course is also concerned with the future of the diagnostic process from the standpoint of the prevalence of bacterial resistance to antibiotics and methods of its detection.
Advanced Immunology:
The course describes an advanced knowledge of cellular and molecular immunobiology and medical immunology. By the end of the course the students will be able to: Knowledge and understanding Identify and summarize the current status of knowledge within areas of cellular and molecular immunology Understand normal regulation of immunity and how aberrations in the regulation can lead to immunological diseases Understand the principles of immunomodulatory treatment and the role of the immune system in development of tumours
Advanced Medical Biochemistry:
Advanced Medical Biochemistry is designed for the MSc. students after general medical biochemistry course. It is enable the student to learn and understand the fundamental aspects related to metabolism of fatty acids and amino acids. The course will introduce water and fat soluble vitamins and diseases related to its disorders.. The course also introduces the basic concepts of the mechanisms of hormones action. The course is designed to provide the student with a strong theoretical background about the purine and pyrimidine nucleotides metabolism, importance of glycoproteins and concepts of integration of metabolism and biochemistry of feed and fasting states.
Biostatistics and research methodology:
This course provides knowledge and skills related to scientific research and orientation to the components of research process, and how to utilize knowledge and skills learnt in developing research proposal, as well as providing an opportunity to critique and/or summarize selected health-related research report. Major emphasis is placed on the critical analysis of theoretical frameworks, research problems cumulative quantitative methodologies comparative research designs, and interpretation of research results. In-depth analysis of concepts related to the research process, such as ethical issues and methodological pitfalls will be explored. Also, this course provides students with an opportunity to learn about statistics and understand how to analyze data. In addition, this course is based on the premise that learning about data analysis is the ultimate goal of a statistic course in a health care field like medical technology. Furthermore, this course will cover descriptive statistics, bivariate inferential statistics, and many widely used multivariate statistics related to health field and evidence-based medical technology.
Advanced Clinical Hematology:
This course provides students with the fundamentals of pathological disorders of the red blood cell (erythrocyte) and white blood cell (leukocyte) systems. The main focus of this course will be the disease processes involving RBCs and WBCs, how these diseases are identified clinically, and the laboratory characteristics of each disorder. The course will be divided into threemajor units: l) Pathophysiology of RBC disorders; 2) Pathophysiology of granulocytic and monocytic disorders; 3) Pathophysiology of lymphocyte disorders.
Basics of Molecular Medicine:
Basics of Molecular Medicine course prepares students for the organ blocks by presenting foundational concepts and principles in molecular and cellular medicine. This includes an analysis of cellular structures and organelles, protein structure and function, nucleic acid biochemistry, replication and repair of DNA, the processes of transcription and translation, regulation of gene expression, modern molecular techniques used for diagnosis and research, the metabolism of carbohydrates, proteins, purines and pyrimidines, and fatty acids, human genetics (Mendelian and mitochondrial inheritance patterns and probabilities, positional cloning, cytogenetics, imprinting, triplet repeat expansions, multifactorial diseases, tumor suppressors, and the relevance of the human genome project to medicine), signal transduction pathways, and elementary nutrition. Mechanisms by which cells sense and respond to their environment will be presented, along with elementary pharmacodynamics, pharmacokinetics, and the absorption, distribution, metabolism and excretion of pharmacologically active compounds. Students will be introduced to some of the basic concepts and principles of immunology and microbiology.
Clinical Virology and Immunology:
The course introduces bacterial, plant and animal viruses and focuses on viruses that infect humans in terms of their structure, classification, methods of transmission, and examination of their reproduction and interaction with the host. Also studying the methods used for diagnosis in addition to the ways used to prevents and control it. The course deals with some viral diseases by studying new research on that topic. Also the course describes an advanced understanding of the principles and mechanisms of the immune system and immune responses in the context of infection, malignancy and immunological disorders. You will also gain insight into a specialist area of laboratory medicine from clinical leaders and researchers at the forefront of immunology. Course content includes :basic and advanced immunology; immune deficiency; immunotherapy; hypersensitivity and allergy; cancer immunology and haematological malignancy; autoimmunity.
Advanced Clinical Chemistry:
The course is designed to introduce some advanced concepts of clinical chemistry related to the chemical analysis of the newborn, fetus and pregnancy, renal calculi, gallstones, pediatric age group, uncommon trace minerals, transplant recipient and vitamins. The student will be able to understand the clinical value of the laboratory tests related to the various topics mentioned above.
Special Topics in Hematology:
This course involves discussion of selected topics in Hematologyical diseases,couses, laboratory diagnostic with emphasis on modern technology uses flow cytometry & Molecular Hematology.
Molecular Epidemiology:
Describes how molecular and epidemiological methods can be used to understand biological processes and infer disease mechanisms. The course will focus on the study of causative genetic and environmental factors at the molecular level to ascertain the origin, distribution, and best strategies for prevention of disease. In communicable disease, the course is concerned with determining the genetic similarities and differences among microbiological isolates. In non-communicable disease, it describes how molecular epidemiology can be used to identify new biomarkers and evaluate their clinical usefulness. The course will highlight advantages and disadvantages with different epidemiological study designs ranging from cross-sectional, cohort, and case-control to family-based designs. After completing the course, students are expected to show the ability to analyze the strengths and weaknesses of different study designs and experimental methods used in molecular epidemiological studies; evaluate the possibility of different methods to provide information about causal inference; evaluate the properties of a biomarker; and evaluate how different "omics"-technologies (genetics, epigenetics, proteomics and metabolomics) can be used as molecular tools in epidemiological studies.
Genetic Engineering:
In this course, students will explore the molecular methods and applications of recombinant DNA technology and the issues regarding their effects on medicine, agriculture, biology, forensics and other areas of technology. The course will concentrate on DNA manipulation techniques used to generate recombinant molecules and transgenic animals and application of recombinant technology to diagnostics and therapeutics and genetically modified organisms. The discussion of potential ethical concerns of genome manipulations will also be included.
Upon completion of the course, students will be able to understand and explain the concept of genetic engineering including the techniques, applications and limitations; to demonstrate the ability to extract knowledge from a variety of sources including journal articles, technical bulletins, product manuals, and drug information sheet to solve problems; and to apply learned knowledge to their future research.
Advanced Topics in Genetics and Genomics:
This course will provide an extensive survey of molecular genetics including molecular and cellular biology and the regulation of gene expression. Applications to human clinical genetics through discussion of relevant case studies will be incorporated. The content of this course will facilitate an understanding of the application of concepts in molecular biology to genetic testing and diagnosis. Students will develop the necessary background knowledge to understand topics covered in additional courses in the genetic counseling master's program including Foundations in Clinical Genetics, Cancer Genetics, Reproductive Genetics, and Medical Genetics.
Molecular Applications in Laboratory Medicine:
This course focuses on the applications of molecular biology in medical practice, with emphasis on laboratory medicine. It will introduce the students to a plethora of fields, in which molecular biology will aid the diagnostic and therapeutic strategies of a range of medical conditions.
By finishing this course, the students will have clarity on various techniques used in the clinical diagnostic laboratory for the diagnosis of various pathogenic situations; will describe the application of molecular medicine in practice; will integrate understanding of molecular medicine (theory) with molecular biology (practice) including to search for, collect, evaluate, interpret and discuss specialized information in relation to medical practice; will demonstrate understanding of ethical aspects of research involving human and/or animal material.
Seminar description
Students are required to present seminars publically in topics of current interest, topics from the core courses, presentation of specific chemical research from recent literature or performed experimentation to members of the medicl science faculty in 20-minute followed by 15-minute question and answer session . Students will be provided with the required skills in developing an overall understanding of the principles of infectious diseases including accepted presentation techniques, listening skills, critical analysis of scientific presentations, participation in scientific discussions in addition to critically reading the scientific literature.
Ethics
Students are expected to cite all sources used in oral and written presentations including all electronic, spoken or print media according to the Columbia Guide to Style (see: http://www.columbia.edu/cu/cup/cgos/idx_basic.html). Cases of plagiarism which is defined as the use of another’s intellectual property without correct citation of the author will be dealt severely with the minimum penalty being a grade of zero for the assignment in question.